As population aging accelerates and health awareness grows, the global oral restoration market continues to expand year over year. Bone graft materials, as critical adjunctive materials, play an increasingly important role in this landscape.
PoroGraft® oral bone graft material, independently developed by Medgen Life Science, is China's first porcine-derived xenograft bone graft material. With its unique advantages, it offers clinicians and patients an entirely new treatment experience.
Unique Biomimetic Porous Structure
PoroGraft® oral bone graft material is primarily composed of hydroxyapatite particles derived from porcine cancellous bone. It features a unique biomimetic porous structure with rougher particle surfaces compared to bovine bone, which better facilitates vascular cell adhesion and migration, and induces stem cell differentiation.
Its calcium-to-phosphorus ratio closely resembles that of human bone, offering high biocompatibility and superior osteogenic activity, providing a material foundation that more closely approximates natural human bone for oral restoration.
Precision Manufacturing Process
Utilizing a gradient temperature-rising calcination method to precisely control sintering temperatures, the manufacturing process preserves the material's natural trabecular pore architecture intact while effectively removing organic components and impurities. This not only ensures excellent osteoconductive performance but also significantly reduces the risk of rejection reactions, enhancing the material's safety and reliability in clinical applications.
Significant Early Bone Formation
PoroGraft® oral bone graft material demonstrates significant early bone formation, accelerating the bone tissue repair process and effectively shortening treatment timelines. Stable bone formation can be achieved within 3 to 6 months, with high bone density, providing solid and reliable bone tissue support for oral restoration.
Clinical data show that PoroGraft® has a pronounced effect in promoting early bone formation, with new bone volume and bone density superior to control groups.
High Purity and Stability
The material achieves a purity of ≥95% and a crystallinity of ≥95%, far exceeding natural bone (approximately 65%). It offers excellent structural stability, degradation resistance, and controllability. It provides stable support during surgery, ensuring long-lasting surgical outcomes. At the same time, it is naturally absorbed by the body and does not require a second surgery for removal, offering patients a safer and more comfortable postoperative experience.
The Unique Advantages of Porcine-Derived Materials
In the medical field, porcine-derived materials hold distinct advantages over other xenograft sources. Pigs share greater genetic similarity with humans, and their organ size, physiological structure, and metabolic characteristics closely resemble those of the human body — resulting in higher biocompatibility and reduced risk of rejection. The microstructure of porcine bone is highly similar to human bone, facilitating easier integration with surrounding bone tissue and promoting autologous bone growth. Furthermore, pigs are relatively easy to raise and grow rapidly, making raw materials readily available — all of which contribute to the unique advantages of porcine bone materials in oral restoration.
Research demonstrates that compared to bovine bone, porcine bone exhibits a pore diameter distribution more similar to that of human bone.
It is precisely these unique advantages of porcine bone that make PoroGraft® oral bone graft material — with its natural biomimicry, efficient osteogenesis, and safety and stability — the ideal choice in the oral bone grafting field.
Looking ahead, Medgen Life Science will continue to pursue innovation and research to provide clinicians and patients with superior products and services, advancing the development of oral medicine in China.
This content is for educational purposes only. Please consult a qualified physician for specific treatment plans.