Hydrophilic Activation — A New Bone Grafting Experience
In oral bone defect repair surgery, the hydrophilic properties of bone filling materials directly impact the convenience of clinical handling and postoperative bone regeneration outcomes. PoroGraft® oral bone filling material delivers an entirely new bone grafting experience for clinicians with its outstanding hydrophilicity and clumping performance.
Excellent Hydrophilicity and Clumping Properties
PoroGraft® bone graft demonstrates exceptional hydrophilic performance. The material particles rapidly adsorb blood and bioactive substances, quickly forming a stable mass upon blood contact. This characteristic provides significant clinical advantages:
- More convenient handling: Particles rapidly absorb blood and form cohesive masses, reducing scatter and enabling surgeons to precisely fill bone defect areas
- Enhanced cell adhesion: Superior hydrophilicity provides an ideal adhesion surface for cells, facilitating early colonization by osteoblasts and vascular endothelial cells
- Accelerated vascularization: Rapidly adsorbed blood creates a natural biological bridge for neovascular ingrowth
Ultra-High Purity Exceeding 95%
PoroGraft® is manufactured using Medgen's proprietary gradient temperature-rising calcination process. While completely preserving the natural bone microstructure, the process effectively removes all organic components and impurities, achieving ultra-high quality standards with purity ≥95% and crystallinity ≥95%.
Ultra-high purity delivers:
- No post-surgical rejection: Thorough removal of organic components that could trigger immune responses
- Strict virus inactivation: Ensuring biological safety
- Stable and reliable structure: High crystallinity provides excellent degradation resistance and controllability
- Natural resorption: The material is naturally absorbed by the body, requiring no secondary surgery for removal
Natural Porcine Bone — Closer to Human Physiology
PoroGraft® is sourced from natural porcine femoral metaphyseal cancellous bone, a choice supported by robust scientific evidence.
Pigs share high genetic similarity with humans, with organ size, physiological structure, and metabolic characteristics closely resembling those of the human body. The microstructure of porcine bone closely matches human skeletal architecture, with a calcium-to-phosphorus ratio similar to human bone and high biocompatibility.
Compared to bovine-derived bone filling materials, porcine-derived PoroGraft® offers distinct advantages:
- Pore size distribution closer to human bone: Porcine bone pore diameter distribution more closely matches human bone
- Higher osteogenic activity: Easier fusion with surrounding bone tissue, promoting autologous bone growth
- Lower rejection risk: Higher biocompatibility reduces the risk of rejection reactions
Clinical Applications
PoroGraft® is indicated for multiple oral bone defect repair scenarios, including extraction site preservation, alveolar ridge augmentation, maxillary sinus lift, peri-implant bone defect repair, and guided bone regeneration (GBR). Stable bone formation is achieved within 3-6 months with high bone density, providing solid and reliable bone tissue support for oral restoration.
As China's first independently developed porcine-derived oral bone graft, PoroGraft® is becoming a trusted choice in dental bone grafting with its outstanding hydrophilic activation performance.